new molecular and immunological diagnostics tools, genomics, vaccine adjuvant, honeybee
Research Area 3: High-throughput, rapid, accurate and easy to use in-field detection technologies
Our main cooperation interest is understanding of animal physiology, biochemistry and immune response, using both experimental and computational methods such as high-throughput DNA sequencing and bioinformatics. The main topics of interest:
-new molecular and immunological diagnostics tools
-vaccine adjuvant studies
We can provide, upon request, a more detailed spectrum of expertise, past projects and collaboration with researchers in the field.
If you have a proposal (or intention of preparing a new one) for ICRAD call, we will be appreciated if you consider us as a partner.
The Laboratory for Biotechnology, Animal health and Immuno-Genomics (BAH-IGm) in Burdur Mehmet Akif Ersoy University (MAKU BAH-IGm Laboratory) was founded by emeritus Prof. Aynur Basalp, as a part of Central Laboratory of Mehmet Akif Ersoy University located in the city of Burdur. Our group’s overall research interests are in the emerging fields of animal diseases, diagnostics and synthetic immunology, which are at the intersection of epidemics, genomics, molecular biotechnology, and vaccine technology.
We apply cellular and molecular methods to study and reprogram immune cells for the purpose of controlling and engineering immunity. These methods consist of studies with experimental animals, hybridoma technology, antibody screening, affinity maturation, protein purification & engineering, toxicology, targeted genome editing, and gene transfer. Our group aims to gain a more comprehensive and quantitative understanding of animal physiology, biochemistry and immune response, using both experimental and computational methods such as high-throughput DNA sequencing and bioinformatics.
MAKU-BAH-IGM Laboratory’s core mission is to develop new molecular and immunological diagnostics tools. For this purpose, we aim to develop novel murine monoclonals, that also can be utilized in ELISA kits, strip kits, biosensors as well as nucleic acid based methods against recurring threats of animal health.
Other studies linked to the research our group:
Vaccine adjuvant studies: Improved immunogenicity is important for an effective vaccination as well as monoclonal antibody production. Dr. Burcu Balkan’s team works in collaborating with our Chemistry and Nanosciences Department to develop novel antigen carriers. They focus on potential application of nanoparticules as delivery systems with target proteins.
Genomics studies: In BAH-IGm Lab, Dr. Sarp KAYA’s team study on phylogeny, population genomics and genomic organization. They prepare customer ready genomic library for Highseq platforms and analysis ddRAdseq, GBS and other type of NGS data sets for several projects. Another research interest of the team is to understand animal genome structure and the new drug design strategies (like phage display) using novel sequencing techniques, such as Next-Generation Sequencing.
Honeybee studies: Collaborating with Ankara University Honeybee Research Laboratory, a sub-group (led by Dr. Hidayet Tutun) is developing new technologies for managing honeybees in presence of parasitic mites, stress and diseases. Primary research focus is developing new cost-effective strategies for controlling parasitic mites, bacterial diseases, and emergent pests. Additionally, they focus on virus transmission, impact of pests and pathogens on colony survival and longevity.